4163-60-4
4163-60-4
Chemical Structure
β-D-Galactose pentaacetate
- CAS No.: 4163-60-4
- Formula:C16H22O11
- Molecular Weight:390.34
IUPAC Name: (2S,3R,4S,5S,6R)-6-(acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate
InChIKey: LPTITAGPBXDDGR-LYYZXLFJSA-N
SMILES: CC(O[C@H]1[C@H]([C@H](O[C@H]([C@@H]1OC(C)=O)OC(C)=O)COC(C)=O)OC(C)=O)=O
Biological Activity: β-D-Galactose pentaacetate is a negative regulator of insulin with plasma membrane penetrating ability and can be hydrolyzed by intracellular esterases. β-D-Galactose pentaacetate inhibits Leucine (HY-N0486)-induced insulin release in Wistar rat islets, potentially preventing excessive insulin release in pathological conditions[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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β-D-Galactose pentaacetate | 99.61% | β-D-Galactose pentaacetate is a negative regulator of insulin with plasma membrane penetrating ability and can be hydrolyzed by intracellular esterases. β-D-Galactose pentaacetate inhibits Leucine (HY-N0486)-induced insulin release in Wistar rat islets, potentially preventing excessive insulin release in pathological conditions. | ||||||||||||||||||||
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References
- [1]. Malaisse WJ, et al. Inhibition of insulin release by alpha- and beta-D-galactose pentaacetate. Int J Mol Med. 1998 Sep;2(3):331-2. [Content Brief]
- [2]. Malaisse WJ, et al. Insulinotropic action of beta-L-glucose pentaacetate. Am J Physiol. 1998 Dec;275(6):E993-E1006. [Content Brief]
- [3]. Kadiata MM, Malaisse WJ. Opposite effects of D-glucose pentaacetate and D-galactose pentaacetate anomers on insulin release evoked by succinic acid dimethyl ester in rat pancreatic islets. Life Sci. 1999;64(9):751-4. [Content Brief]
