418794-42-0
418794-42-0
Chemical Structure
Ronomilast
Synonym(s): Elbimilast; ELB353
- CAS No.: 418794-42-0
- Formula:C21H15Cl2FN4O2
- Molecular Weight:445.27
IUPAC Name: N-(3,5-dichloropyridin-4-yl)-2-(1-(4-fluorobenzyl)-2,7a-dihydro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-oxoacetamide
InChIKey: FGPRLLZDEDRQEY-UHFFFAOYSA-N
SMILES: FC1=CC=C(CN2C(N=CC=C3)C3=C(C(C(NC4=C(Cl)C=NC=C4Cl)=O)=O)C2)C=C1
Biological Activity: Ronomilast (Elbimilast; ELB353) is an orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 3 nM. Revamilast can be used for research to inflammation related diseases[1].
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Ronomilast | Ronomilast (Elbimilast; ELB353) is an orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 3 nM. Revamilast can be used for research to inflammation related diseases. | |||||||||||||||||||||
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