420106-23-6

ATXN1-MED15 PPI-IN-1 Chemical Structure
420106-23-6

Chemical Structure

ATXN1-MED15 PPI-IN-1

  • CAS No.: 420106-23-6
  • Formula:C29H21NO4
  • Molecular Weight:447.48

InChIKey: XNYMPHBZSUCWTP-KNTRCKAVSA-N

SMILES: O=C(/C=C/C1=CC=C(NC(C2=C(C3=CC=CC=C3C(O)=O)C=CC=C2)=O)C=C1)C4=CC=CC=C4

Biological Activity: ATXN1-MED15 PPI-IN-1 (compound 5755483) is an inhibitor of ATXN1/MED15. ATXN1-MED15 PPI-IN-1 binds to ATXN1 residues 99-163 and inhibits both the interaction between ATXN1 and MED15, as well as the dimerization of polyQ-expanded ATXN1. ATXN1-MED15 PPI-IN-1 can be used for study of Spinocerebellar ataxia type 1[1].

Cat. No. Product Name Purity Description Pricing
HY-173353
ATXN1-MED15 PPI-IN-1 ATXN1-MED15 PPI-IN-1 (compound 5755483) is an inhibitor of ATXN1/MED15. ATXN1-MED15 PPI-IN-1 binds to ATXN1 residues 99-163 and inhibits both the interaction between ATXN1 and MED15, as well as the dimerization of polyQ-expanded ATXN1. ATXN1-MED15 PPI-IN-1 can be used for study of Spinocerebellar ataxia type 1.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References