422546-87-0
Chemical Structure
NFAT Inhibitor-2
- CAS No.: 422546-87-0
- Formula:C22H20F2N2O4S
- Molecular Weight:446.47
IUPAC Name: 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-(N-(4-methoxybenzyl)sulfamoyl)benzamide
InChIKey: UILNVCFXMNSVLA-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C)C(F)=C1)C2=CC=C(F)C(S(=O)(NCC3=CC=C(OC)C=C3)=O)=C2
Biological Activity: NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NFAT Inhibitor-2 | 98.42% | NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17). | ||||||||||||||||||||
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