431996-53-1
Chemical Structure
Filastatin
- CAS No.: 431996-53-1
- Formula:C18H18ClN3O3
- Molecular Weight:359.81
IUPAC Name: (3-chloro-4-methylphenyl)(4-(4-nitrophenyl)piperazin-1-yl)methanone
InChIKey: PNECWWUOUHGWQG-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
Biological Activity: Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Filastatin | 98.83% | Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect. | ||||||||||||||||||||
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