439588-33-7
439588-33-7
Chemical Structure
Hsp90-IN-34
- CAS No.: 439588-33-7
- Formula:C22H14F2N6O
- Molecular Weight:416.38
SMILES: N#CC1=C(N)OC2=C(C1C3=CNN=C3C4=CC=C(F)C=C4)C(C5=CC=C(F)C=C5)=NN2
Biological Activity: Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90/Aha1 (KDapp=23.5 µM). Hsp90-IN-34 modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1[1].
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Hsp90-IN-34 | Hsp90-IN-34 (compound HAM-1) is a compound that inhibits the Aha1-Hsp90 chaperone complex with a high affinity for Hsp90/Aha1 (KDapp=23.5 µM). Hsp90-IN-34 modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1. | |||||||||||||||||||||
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