439903-56-7
439903-56-7
Chemical Structure
DRF-8417
- CAS No.: 439903-56-7
- Formula:C15H17N3O5S
- Molecular Weight:351.38
InChIKey: VTVGNCICMNIBNG-LBPRGKRZSA-N
SMILES: O=C1N(C2=CC=C(N3C(OCC3)=O)C=C2)C[C@@H](O1)CNC(OC)=S
Biological Activity: DRF-8417, an oxazolidinone antibiotic, is active against Gram-positive and fastidious Gram-negative bacteria. DRF 8417 exhibits potent activity against Gram-positive pathogens with MIC50 and MIC90 values ranging from 0.06 to 1 mg/L[1][2].
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DRF-8417 | DRF-8417, an oxazolidinone antibiotic, is active against Gram-positive and fastidious Gram-negative bacteria. DRF 8417 exhibits potent activity against Gram-positive pathogens with MIC50 and MIC90 values ranging from 0.06 to 1 mg/L. | |||||||||||||||||||||
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References
- [1]. K Sreenivas, et al. In vitro and in vivo antibacterial evaluation of DRF 8417, a new oxazolidinone. J Antimicrob Chemother. 2007 Jul;60(1):159-61. [Content Brief]
- [2]. Mahesh V. Patel, et al. Indian Discovery Effort in the Quest of Novel Antibiotics. Drug Discovery and Drug Development. 11 February 2021.
