439943-59-6
439943-59-6
Chemical Structure
Canfosfamide hydrochloride
- CAS No.: 439943-59-6
- Formula:C26H41Cl5N5O10PS
- Molecular Weight:823.94
IUPAC Name: N5-((R)-3-((2-((bis(bis(2-chloroethyl)amino)phosphoryl)oxy)ethyl)sulfonyl)-1-(((R)-carboxy(phenyl)methyl)amino)-1-oxopropan-2-yl)-L-glutamine hydrochloride
InChIKey: NECZZOFFLFZNHL-XVGZVFJZSA-N
SMILES: ClCCN(CCCl)P(N(CCCl)CCCl)(OCCS(C[C@H](NC(CC[C@H](N)C(O)=O)=O)C(N[C@H](C1=CC=CC=C1)C(O)=O)=O)(=O)=O)=O.Cl
Biological Activity: Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.
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Canfosfamide hydrochloride | Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative. | |||||||||||||||||||||
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