443144-27-2
443144-27-2
Chemical Structure
Pruvanserin hydrochloride
Synonym(s): EMD 281014; LY 2422347 hydrochloride
- CAS No.: 443144-27-2
- Formula:C22H22ClFN4O
- Molecular Weight:412.89
IUPAC Name: 7-(4-(4-fluorophenethyl)piperazine-1-carbonyl)-1H-indole-3-carbonitrile hydrochloride
InChIKey: UYGNZRVLPYZLTF-UHFFFAOYSA-N
SMILES: N#CC1=CNC2=C1C=CC=C2C(N3CCN(CC3)CCC4=CC=C(C=C4)F)=O.Cl
Biological Activity: Pruvanserin hydrochloride (EMD 281014) is a selective serotonin 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors. Pruvanserin (hydrochloride) can be used for the research of schizophrenia[1].
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Pruvanserin hydrochloride | Pruvanserin hydrochloride (EMD 281014) is a selective serotonin 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors. Pruvanserin (hydrochloride) can be used for the research of schizophrenia. | |||||||||||||||||||||
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