445010-62-8
Chemical Structure
CKD-711
- CAS No.: 445010-62-8
- Formula:C25H43NO20
- Molecular Weight:677.60
IUPAC Name: (2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((1R,2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)-7-oxabicyclo[4.1.0]heptan-2-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal
InChIKey: ZMFYXLYDFOQLDO-NVGHVDPISA-N
SMILES: OC[C@]12[C@@H]([C@@H]([C@H](O)[C@@H](O)[C@@H]2O)N[C@]3([H])[C@H](O[C@H](O[C@]4([H])[C@H](O[C@H](O[C@@]([C@H](O)CO)([H])[C@H](O)[C@@H](O)C=O)[C@H](O)[C@H]4O)CO)[C@H](O)[C@H]3O)CO)O1
Biological Activity: CKD-711 is an orally active aminooligosaccharide α-glucosidase inhibitor with an IC50 of 78 μg/mL. CKD-711 also inhibits porcine intestinal maltase and sucrose with IC50 values of 2.5 and 0.5 μg/mL. CKD-711 shows selective antibacterial activity against Comamonas terrigena. CKD-711 can be used for the researches of infection and metabolic disease, such as diabetes[1].
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CKD-711 | CKD-711 is an orally active aminooligosaccharide α-glucosidase inhibitor with an IC50 of 78 μg/mL. CKD-711 also inhibits porcine intestinal maltase and sucrose with IC50 values of 2.5 and 0.5 μg/mL. CKD-711 shows selective antibacterial activity against Comamonas terrigena. CKD-711 can be used for the researches of infection and metabolic disease, such as diabetes. | |||||||||||||||||||||
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