452056-93-8
452056-93-8
Chemical Structure
CBS-3408
- CAS No.: 452056-93-8
- Formula:C18H17FN4OS
- Molecular Weight:356.42
InChIKey: CJKGORBZVWDVRY-UHFFFAOYSA-N
SMILES: O=C(C)NC1=NC=CC(C2=C(C3=CC=C(C=C3)F)N=C(N2C)SC)=C1
Biological Activity: CBS-3408 is an orally active p38α MAPK inhibitor. CBS-3408 inhibits the release of TNFα and IL-1β. CBS-3408 reduces the disease severity of arthritis in mice. CBS-3408 inhibits TNFα release in a rat endotoxemia model. CBS-3408 can be used in studies related to endotoxemia and arthritis[1].
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CBS-3408 | CBS-3408 is an orally active p38α MAPK inhibitor. CBS-3408 inhibits the release of TNFα and IL-1β. CBS-3408 reduces the disease severity of arthritis in mice. CBS-3408 inhibits TNFα release in a rat endotoxemia model. CBS-3408 can be used in studies related to endotoxemia and arthritis. | |||||||||||||||||||||
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