452105-23-6
452105-23-6
Chemical Structure
(Z)-SU14813
- CAS No.: 452105-23-6
- Formula:C23H27FN4O4
- Molecular Weight:442.48
IUPAC Name: (S,Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
InChIKey: CTNPALGJUAXMMC-PMFHANACSA-N
SMILES: O=C1NC2=CC=C(C=C2/C1=C/C3=C(C(C(NC[C@@H](CN4CCOCC4)O)=O)=C(N3)C)C)F
Biological Activity: (Z)-SU14813 is an analog of SU14813 (HY-10501). SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT[1].
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(Z)-SU14813 | (Z)-SU14813 is an analog of SU14813 (HY-10501). SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT. | |||||||||||||||||||||
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