4605-14-5
4605-14-5
Chemical Structure
Norspermine
- CAS No.: 4605-14-5
- Formula:C9H24N4
- Molecular Weight:188.31
IUPAC Name: N1,N1'-(propane-1,3-diyl)bis(propane-1,3-diamine)
InChIKey: ZAXCZCOUDLENMH-UHFFFAOYSA-N
SMILES: NCCCNCCCNCCCN
Biological Activity: Norspermine is a synthetic tetraamine polyamine and a structural analog of Thermospermine (HY-151224), discovered in Thermodesulfobacterium thermophilum and Thermus thermophilus. Norspermine can partially substitute for Thermospermine function during growth and development, and is used in research on tumors, infections, and other conditions[1][2].
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Norspermine | 99.94% | Norspermine is a synthetic tetraamine polyamine and a structural analog of Thermospermine (HY-151224), discovered in Thermodesulfobacterium thermophilum and Thermus thermophilus. Norspermine can partially substitute for Thermospermine function during growth and development, and is used in research on tumors, infections, and other conditions. | ||||||||||||||||||||
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References
- [1]. Li B, et al. Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N-aminopropylagmatine synthases. The Journal of biological chemistry. 2024 May;300(5):107281. [Content Brief]
- [2]. Perevoshchikova KA, et al. Symmetric lipophilic polyamines exhibiting antitumor activity. Bioorganic & medicinal chemistry. 2022 Dec 15;76:117089. [Content Brief]
