467214-21-7
Chemical Structure
Alvespimycin hydrochloride
Synonym(s): 17-DMAG hydrochloride; KOS-1022 hydrochloride; BMS 826476
- CAS No.: 467214-21-7
- Formula:C32H49ClN4O8
- Molecular Weight:653.21
IUPAC Name: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((2-(dimethylamino)ethyl)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate hydrochloride
InChIKey: DFSYBWLNYPEFJK-IHLRWNDRSA-N
SMILES: C/C1=C\C=C/[C@@H]([C@H](/C(C)=C/[C@@H]([C@H]([C@H](C[C@@H](CC(C(C(NC1=O)=CC2=O)=O)=C2NCCN(C)C)C)OC)O[H])C)OC(N)=O)OC.Cl
Biological Activity: Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Alvespimycin hydrochloride | 98.80% | Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
