47308-67-8
Chemical Structure
Methoxyfenoterol
- CAS No.: 47308-67-8
- Formula:C18H23NO4
- Molecular Weight:317.38
InChIKey: WHAUNCTVVNUUIP-UHFFFAOYSA-N
SMILES: OC1=CC(C(CNC(CC2=CC=C(C=C2)OC)C)O)=CC(O)=C1
Biological Activity: Methoxyfenoterol is a β2-adrenergic receptor agonist. Methoxyfenoterol stimulates intracellular cAMP accumulation, inhibits tumor cell proliferation, induces G1 cell cycle arrest, upregulates cyclin-dependent kinase inhibitor p27, downregulates cyclin D1 and cyclin A, and inhibits Akt phosphorylation. Methoxyfenoterol crosses the blood-brain barrier and inhibits growth of astrocytoma xenografts. Methoxyfenoterol can be used for the research of astrocytoma, glioblastoma[1].
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Methoxyfenoterol | Methoxyfenoterol is a β2-adrenergic receptor agonist. Methoxyfenoterol stimulates intracellular cAMP accumulation, inhibits tumor cell proliferation, induces G1 cell cycle arrest, upregulates cyclin-dependent kinase inhibitor p27, downregulates cyclin D1 and cyclin A, and inhibits Akt phosphorylation. Methoxyfenoterol crosses the blood-brain barrier and inhibits growth of astrocytoma xenografts. Methoxyfenoterol can be used for the research of astrocytoma, glioblastoma. | |||||||||||||||||||||
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