476148-82-0
476148-82-0
Chemical Structure
MCI-225 hydrate hydrochloride
Synonym(s): DDP-225 hydrate hydrochloride
- CAS No.: 476148-82-0
- Formula:C17H20ClFN4OS
- Molecular Weight:382.88
IUPAC Name: 4-(2-fluorophenyl)-6-methyl-2-(piperazin-1-yl)thieno[2,3-d]pyrimidine hydrochloride hydrate
InChIKey: SAURKKOJWIFYSR-UHFFFAOYSA-N
SMILES: CC1=CC2=C(N=C(N=C2S1)N3CCNCC3)C4=CC=CC=C4F.Cl.O
Biological Activity: MCI-225 (DDP-225) hydrate hydrochloride is a selective and orally active noradrenaline (NA) reuptake inhibitor with 5-HT3 receptor antagonism. MCI-225 hydrate hydrochloride has antidepressant-like and anxiolytic-like properties. MCI-225 hydrate hydrochloride can be used for the study of anxiety disorder[1][2].
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MCI-225 hydrate hydrochloride | MCI-225 (DDP-225) hydrate hydrochloride is a selective and orally active noradrenaline (NA) reuptake inhibitor with 5-HT3 receptor antagonism. MCI-225 hydrate hydrochloride has antidepressant-like and anxiolytic-like properties. MCI-225 hydrate hydrochloride can be used for the study of anxiety disorder. | |||||||||||||||||||||
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References
- [1]. Eguchi J, et al. The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism. Pharmacol Biochem Behav. 2001 Apr;68(4):677-83. [Content Brief]
- [2]. Eguchi J, et al. Effects of a novel compound MCI-225 on impaired learning and memory in rats. Pharmacol Biochem Behav. 1994 Jun;48(2):345-9. [Content Brief]
