484-27-5
484-27-5
Chemical Structure
Visnaginone
- CAS No.: 484-27-5
- Formula:C11H10O4
- Molecular Weight:206.19
InChIKey: JGNYBYBMPAOPJD-UHFFFAOYSA-N
SMILES: CC(C1=C(O)C=C(OC=C2)C2=C1OC)=O
Biological Activity: Visnaginone is the derivative of Visnagin (HY-N1082). Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles[1][2][3].
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Visnaginone | Visnaginone is the derivative of Visnagin (HY-N1082). Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles. | |||||||||||||||||||||
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References
- [1]. Abu-Hashem AA, et al. Synthesis of Novel Benzodifuranyl; 1,3,5-Triazines; 1,3,5-Oxadiazepines; and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents. Molecules. 2020 Jan 5;25(1):220. [Content Brief]
- [2]. Radim Vrzal, et al. Khellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cells. PLoS One. 2013 Sep 19;8(9):e74917. [Content Brief]
- [3]. Lakshmi Priya Pasari, et al. Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction. Biomed Pharmacother. 2019 Apr;112:108629. [Content Brief]
