485319-41-3
485319-41-3
Chemical Structure
CCT070535
- CAS No.: 485319-41-3
- Formula:C20H13Cl2N3O2
- Molecular Weight:398.24
InChIKey: NPHWSYSBGVFAIS-UHFFFAOYSA-N
SMILES: O=C1C(CC2=CC=CC=C2)=C([O-])[N+]3=NC(Cl)=CC=C3N1C4=CC=C(Cl)C=C4
Biological Activity: CCT070535 blocks TCF-dependent transcription at the TCF level, with GI50 values of 17.6 μM, 11.1 μM, 11.8 μM and 13.4 μM in HT29 (APC mutant), HCT116 (oncogenic β-catenin), SW480 (APC mutant) and SNU475 (Axin mutant) cells, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCT070535 | CCT070535 blocks TCF-dependent transcription at the TCF level, with GI50 values of 17.6 μM, 11.1 μM, 11.8 μM and 13.4 μM in HT29 (APC mutant), HCT116 (oncogenic β-catenin), SW480 (APC mutant) and SNU475 (Axin mutant) cells, respectively. | |||||||||||||||||||||
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