487-26-3
487-26-3
Chemical Structure
Flavanone
- CAS No.: 487-26-3
- Formula:C15H12O2
- Molecular Weight:224.26
IUPAC Name: 2-phenylchroman-4-one
InChIKey: ZONYXWQDUYMKFB-UHFFFAOYSA-N
SMILES: O=C1CC(C2=CC=CC=C2)OC3=CC=CC=C13
Biological Activity: Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy[1][2].
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Flavanone | 99.73% | Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy. | ||||||||||||||||||||
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Flavanone (Standard) | ≥98% | Flavanone (Standard) is the analytical standard of Flavanone. This product is intended for research and analytical applications. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). lavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy. | ||||||||||||||||||||
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References
- [1]. JT Kellis Jr, et al. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep. 225 (4666):1032-1034.
- [2]. Hsiao YC, et al., Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway. Chem Biol Interact. 2007 May 1;167(3):193-206. [Content Brief]
