495-78-3
495-78-3
Chemical Structure
Melilotic acid
- CAS No.: 495-78-3
- Formula:C9H10O3
- Molecular Weight:166.18
IUPAC Name: 3-(2-hydroxyphenyl)propanoic acid
InChIKey: CJBDUOMQLFKVQC-UHFFFAOYSA-N
SMILES: O=C(O)CCC1=CC=CC=C1O
Biological Activity: Melilotic acid (3-(2-hydroxyphenyl)-propanoic acid) is an orally active compound. Melilotic acid can be isolated from the bark of Chinese cinnamon. Melilotic acid has a significant inhibitory effect on gastric ulcers induced by serotonin (HY-B1473A), phenylbutazone (HY-B0230), ethanoyl, and water immersion stress[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Melilotic acid | 99.86% | Melilotic acid (3-(2-hydroxyphenyl)-propanoic acid) is an orally active compound. Melilotic acid can be isolated from the bark of Chinese cinnamon. Melilotic acid has a significant inhibitory effect on gastric ulcers induced by serotonin (HY-B1473A), phenylbutazone (HY-B0230), ethanoyl, and water immersion stress. | ||||||||||||||||||||
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Melilotic acid (Standard) | 99.92% | Melilotic acid (Standard) is an analytical standard for Melilotic acid (HY-W017158). This product is intended for research and analytical applications. Melilotic acid (3-(2-hydroxyphenyl)-propanoic acid) is an orally active compound. Melilotic acid can be isolated from the bark of Chinese cinnamon. Melilotic acid has a significant inhibitory effect on gastric ulcers induced by serotonin (HY-B1473A), phenylbutazone (HY-B0230), ethanoyl, and water immersion stress. | ||||||||||||||||||||
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DL-O-Tyrosine | 99.14% | DL-O-Tyrosine is a tyrosine derivative. | ||||||||||||||||||||
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3-(2,4-Dihydroxyphenyl)propanoic acid | 99.39% | 3-(2,4-Dihydroxyphenyl) propanoic acid (DPPacid) is a competitive Tyrosinase inhibitor. It exhibits an IC50 value of 3.02 μM against mushroom tyrosinase with L-tyrosine as the substrate, an IC50 value of 62 μM with DL-DOPA as the substrate, and a Ki value of 11.5 μM. 3-(2,4-Dihydroxyphenyl) propanoic acid shows no DPPH radical scavenging activity. It can be used in studies related to ultraviolet B (UVB)-induced hyperpigmentation. | ||||||||||||||||||||
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Dihydrocaffeic acid | 99.86% | Dihydrocaffeic acid is a microbial metabolite of flavonoids. Dihydrocaffeic acid scavenges intracellular ROS and increases nitric oxide synthase activity. Dihydrocaffeic acid reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Dihydrocaffeic acid has antioxidant, anti-inflammatory and anti-cartilage degradation activities. | ||||||||||||||||||||
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3-(3-Hydroxyphenyl)propionic acid | 99.67% | 3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases. | ||||||||||||||||||||
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Desaminotyrosine | 99.81% | Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. | ||||||||||||||||||||
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2-Hydroxyphenylacetic acid | 98.79% | 2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia. | ||||||||||||||||||||
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2-Hydroxyphenylethanol | 2-Hydroxyphenylethanol is a molecular chaperone that rescues misfolded P123S mutant pendrin, promoting translocation from the cytoplasm to the plasma membrane. 2-Hydroxyphenylethanol can be used for the research of pendred syndrome. | |||||||||||||||||||||
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4-(4-Hydroxyphenyl)butanoic acid | 98.82% | 4-(4-Hydroxyphenyl)butanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Hydrocinnamic acid | 99.95% | Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities. | ||||||||||||||||||||
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Hydrocinnamic acid-2,3-13C2 | Hydrocinnamic acid-2,3-13C2 is the 13C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities. | |||||||||||||||||||||
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References
- [1]. LEVY CC, et al. THE METABOLISM OF COUMARIN BY A MICROORGANISM. II. THE REDUCTION OF O-COUMARIC ACID TO MELILOTIC ACID. Biochemistry. 1964 Dec;3:1944-7. [Content Brief]
- [2]. Tanaka S, et al. Antiulcerogenic compounds isolated from Chinese cinnamon. Planta Med. 1989 Jun;55(3):245-8. [Content Brief]
