500794-88-7
500794-88-7
Chemical Structure
TR antagonist 1
- CAS No.: 500794-88-7
- Formula:C25H23Br2NO4
- Molecular Weight:561.26
IUPAC Name: (E)-3-(3,5-dibromo-4-(4-hydroxy-3-isopropyl-5-(2-(pyridin-4-yl)vinyl)phenoxy)phenyl)propanoic acid
InChIKey: JFQSWHAFVANRQE-HWKANZROSA-N
SMILES: O=C(O)CCC1=CC(Br)=C(OC2=CC(/C=C/C3=CC=NC=C3)=C(O)C(C(C)C)=C2)C(Br)=C1
Biological Activity: TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively.
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TR antagonist 1 | 99.49% | TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively. | ||||||||||||||||||||
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TR antagonist 1 (Standard) | ≥98% | TR antagonist 1 (Standard) is the analytical standard of TR antagonist 1 (HY-111443). This product is intended for research and analytical applications. TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively. | ||||||||||||||||||||
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