503468-95-9
503468-95-9
Chemical Structure
KU-57788
Synonym(s): NU7441
- CAS No.: 503468-95-9
- Formula:C25H19NO3S
- Molecular Weight:413.49
IUPAC Name: 8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one
InChIKey: JAMULYFATHSZJM-UHFFFAOYSA-N
SMILES: O=C1C=C(N2CCOCC2)OC3=C1C=CC=C3C4=CC=CC5=C4SC6=C5C=CC=C6
Biological Activity: KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KU-57788 | 99.95% | KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively. | ||||||||||||||||||||
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KU-57788 (Standard) | ≥98% | KU-57788 (Standard) is the analytical standard of KU-57788 (HY-11006). This product is intended for research and analytical applications. KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively. | ||||||||||||||||||||
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