5051-62-7
5051-62-7
Chemical Structure
Guanabenz
- CAS No.: 5051-62-7
- Formula:C8H8Cl2N4
- Molecular Weight:231.08
IUPAC Name: (E)-2-(2,6-dichlorobenzylidene)hydrazine-1-carboximidamide
InChIKey: WDZVGELJXXEGPV-YIXHJXPBSA-N
SMILES: ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1
Biological Activity: Guanabenz is an orally active α-2-adrenoceptor agonist. Guanabenz has antihypertensive effect and antiparasitic activity. Guanabenz interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz also is used for the research of high blood pressure[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Guanabenz | 99.85% | Guanabenz is an orally active α-2-adrenoceptor agonist. Guanabenz has antihypertensive effect and antiparasitic activity. Guanabenz interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz also is used for the research of high blood pressure. | ||||||||||||||||||||
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References
- [1]. Christiane Neuber, et al. Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes. PLoS One. 2014 Jun 3;9(6):e98893. [Content Brief]
- [2]. Jennifer Martynowicz, et al. Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation. mBio. 2019 Apr 30;10(2):e00381-19. [Content Brief]
- [3]. T Baum, et al. Studies on the centrally mediated hypotensive activity of guanabenz. Eur J Pharmacol. 1976 May;37(1):31-44. [Content Brief]
