50665-54-8
50665-54-8
Chemical Structure
WR 146459
- CAS No.: 50665-54-8
- Formula:C21H18Cl2F3NO
- Molecular Weight:428.27
InChIKey: GEHCOXATBTVZDU-UHFFFAOYSA-N
SMILES: OC(C1=CC2=C(C3=CC(C(F)(F)F)=CC=C13)C=C(Cl)C=C2Cl)C4CCCCN4
Biological Activity: WR 146459 is an orally active 9-phenanthrenecarbinol and antimalarial agent. WR 146459 bears a 2-piperidyl substituent on its 9-carbinol moiety. WR 146459 inhibits hypoxanthine uptake by Plasmodium falciparum strains, reducing parasite viability. WR 146459 can be used for the research of malaria[1].
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WR 146459 | WR 146459 is an orally active 9-phenanthrenecarbinol and antimalarial agent. WR 146459 bears a 2-piperidyl substituent on its 9-carbinol moiety. WR 146459 inhibits hypoxanthine uptake by Plasmodium falciparum strains, reducing parasite viability. WR 146459 can be used for the research of malaria. | |||||||||||||||||||||
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