507-89-1
507-89-1
Chemical Structure
Pennogenin
- CAS No.: 507-89-1
- Formula:C27H42O4
- Molecular Weight:430.62
IUPAC Name: (4S,5'R,6aR,6bS,8aS,8bS,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,11a,12,12a,12b-octadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4,8b(9H)-diol
InChIKey: SYYHBUHOUUETMI-WJOMMTHPSA-N
SMILES: O[C@@]([C@](O[C@]1(OC2)CC[C@H]2C)([H])C[C@@]3([H])[C@@](CC=C(C4)[C@@]5(CC[C@@H]4O)C)([H])[C@]5([H])CC6)([C@@H]1C)[C@]36C
Biological Activity: Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pennogenin | 99.90% | Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS. | ||||||||||||||||||||
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17,17-Ethylendioxyandrost-5-en-3β-ol | 17,17-Ethylendioxyandrost-5-en-3β-ol is an HSV-1 inhibitor, with an EC50 value of 629 μM. 17,17-Ethylendioxyandrost-5-en-3β-ol can be used in research related to viral infections. |
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Diosgenin | 99.92% | Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway. Diosgenin is an exogenous activator of Pdia3/ERp57. Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression. | ||||||||||||||||||||
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Ruscogenin (Standard) | ≥98% | Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity. | ||||||||||||||||||||
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Diosgenin glucoside (Standard) | 99.87% | Diosgenin glucoside (Standard) is the analytical standard of Diosgenin glucoside. This product is intended for research and analytical applications. Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis . | ||||||||||||||||||||
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Polyphyllin VI | 99.74% | Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer. | ||||||||||||||||||||
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(25S)-Ruscogenin | (25S)-Ruscogenin is a steroidal sapogenin found in the tubers of Liriope spicata. | |||||||||||||||||||||
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Yamogenin (Standard) | ≥98% | Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC50 of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer. | ||||||||||||||||||||
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Mannioside A | Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect. | |||||||||||||||||||||
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Periplocoside N | 97.53% | Periplocoside N, a pregnane glycoside isolated from root powder of Periploca sepium, possesses insecticidal activities against the red imported fire ant. | ||||||||||||||||||||
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25(R,S)-Ruscogenin | 99.83% | Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway. And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su | ||||||||||||||||||||
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