51020-87-2
51020-87-2
Chemical Structure
Licarin B
Synonym(s): (-)-Licarin B
- CAS No.: 51020-87-2
- Formula:C20H20O4
- Molecular Weight:324.37
IUPAC Name: 5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
InChIKey: DMMQXURQRMNSBM-YZAYTREXSA-N
SMILES: COC1=C(O[C@@H](C2=CC=C3C(OCO3)=C2)[C@@H]4C)C4=CC(/C=C/C)=C1
Biological Activity: Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[1][2][3].
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Licarin B | 99.93% | Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway. | ||||||||||||||||||||
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Licarin B-d4 | Licarin B-d4 is the deuterium labeled Licarin B (HY-N0479). Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway. | |||||||||||||||||||||
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References
- [1]. Kim YB, et al. The crystal structure of licarin-B, (C20H20O4), a component of the seeds of Myristica fragrans. Arch Pharm Res. 1991 Mar;14(1):1-6. [Content Brief]
- [2]. G. L. Shyni, et al. Licarin B from Myristica fragrans improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes. RSC Adv. 2016.
- [3]. Cao GY, et al. New inhibitors of nitric oxide production from the seeds of Myristica fragrans. Food Chem Toxicol. 2013 Dec;62:167-71. [Content Brief]
