51352-87-5
Chemical Structure
PRL-8-53
- CAS No.: 51352-87-5
- Formula:C18H22ClNO2
- Molecular Weight:319.83
IUPAC Name: methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate hydrochloride
InChIKey: HLBBSWSJLPLPRU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC(CCN(CC2=CC=CC=C2)C)=C1)OC.Cl
Biological Activity: PRL-8-53 is an orally active, blood-brain barrier-permeable benzoate derivative with potent spasmolytic activity and central nervous system regulatory activity. PRL-8-53 acts on dopamine, serotonin and cholinergic-related targets, enhances dopamine activity, partially inhibits serotonin function and elicits cholinergic responses, thereby maintaining neurotransmitter balance in the central nervous system. PRL-8-53 improves learning ability, short-term memory and long-term memory in animals. PRL-8-53 can be used in central nervous system-related research[1][2].
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PRL-8-53 | PRL-8-53 is an orally active, blood-brain barrier-permeable benzoate derivative with potent spasmolytic activity and central nervous system regulatory activity. PRL-8-53 acts on dopamine, serotonin and cholinergic-related targets, enhances dopamine activity, partially inhibits serotonin function and elicits cholinergic responses, thereby maintaining neurotransmitter balance in the central nervous system. PRL-8-53 improves learning ability, short-term memory and long-term memory in animals. PRL-8-53 can be used in central nervous system-related research. | |||||||||||||||||||||
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References
- [1]. Hansl NR, et al. PRL-8-53: enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent. Psychopharmacology (Berl). 1978;56(3):249-253. [Content Brief]
- [2]. Hansl NR. A novel spasmolytic and CNS active agent 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride. Experientia. 1974 Mar 01;30:271-272.
