5195-71-1
5195-71-1
Chemical Structure
HMGB1-IN-3
- CAS No.: 5195-71-1
- Formula:C31H46O4
- Molecular Weight:482.69
InChIKey: LHVOTBCQBLBMAB-GJIZTULQSA-N
SMILES: C[C@]1(C(OC)=O)CC[C@]([C@@]2([H])C1)(C)CC[C@@](C2=C3)(C)[C@]4(C)CC[C@@]5([H])C(C)(C)C(CC[C@]5(C)[C@@]4([H])C3=O)=O
Biological Activity: HMGB1-IN-3 (compound E) is a glycyrrhizic acid derivative with strong inhibitory activity against HMGB1 (high mobility group protein 1) and can be used in the study of intracerebral hemorrhage[1].
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HMGB1-IN-3 | HMGB1-IN-3 (compound E) is a glycyrrhizic acid derivative with strong inhibitory activity against HMGB1 (high mobility group protein 1) and can be used in the study of intracerebral hemorrhage. | |||||||||||||||||||||
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References
- [1]. Machida, et al. "A Glycyrrhizin Derivative with a More Potent Inhibitory Activity against High-Mobility Group Box 1 Efficiently Discovered by Chemical Synthesis Inspired by the Bioconversion Products of an Endophytic Fungus Isolated from Licorice." Journal of Medicinal Chemistry (2024). [Content Brief]
