521972-99-6
521972-99-6
Chemical Structure
Protonstatin-1
- CAS No.: 521972-99-6
- Formula:C8H5NO2S2
- Molecular Weight:211.26
IUPAC Name: (Z)-5-(furan-2-ylmethylene)-2-thioxothiazolidin-4-one
InChIKey: ISSUVJNRFWFRIV-XQRVVYSFSA-N
SMILES: O=C1NC(S/C1=C\C2=CC=CO2)=S
Biological Activity: Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Protonstatin-1 | 98.47% | Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity. | ||||||||||||||||||||
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References
- [1]. Yongqing Yang, et al. Testing the polar auxin transport model with a selective plasma membrane H+ -ATPase inhibitor. J Integr Plant Biol. 2022 Jun;64(6):1229-1245. [Content Brief]
- [2]. Yongqing Yang, et al. Screening of protonstatin-1 (PS-1) analogs for improved inhibitors of plant plasma membrane H+-ATPase activity. Front Plant Sci. 2022 Oct 12:13:973471. [Content Brief]
