52498-32-5
Chemical Structure
Boc-N-methyl-L-isoleucine
Synonym(s): Boc-N-Me-Ile-OH
- CAS No.: 52498-32-5
- Formula:C12H23NO4
- Molecular Weight:245.32
IUPAC Name: N-(tert-butoxycarbonyl)-N-methyl-L-isoleucine
InChIKey: HTBIAUMDQYXOFG-IUCAKERBSA-N
SMILES: CC[C@H](C)[C@H](N(C)C(=O)OC(C)(C)C)C(=O)O
Biological Activity: Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a Boc-protected N-methylated derivative of L-isoleucine (HY-N0771), as well as a protected amino acid building block[1][2].
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Boc-N-methyl-L-isoleucine | 99.17% | Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a Boc-protected N-methylated derivative of L-isoleucine (HY-N0771), as well as a protected amino acid building block. | ||||||||||||||||||||
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NSC 135130 | 97.10% | NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates. | ||||||||||||||||||||
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(2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid | 98.0% | (2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid is a valine derivative. | ||||||||||||||||||||
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N-Boc-MeVal | N-Boc-MeVal is an ADC linker with BOC protecting group. | |||||||||||||||||||||
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(tert-Butoxycarbonyl)-D-leucine | 99.95% | (tert-Butoxycarbonyl)-D-leucine is a leucine derivative. | ||||||||||||||||||||
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Boc-L-Leu-OH | 97.0% | Boc-L-Leu-OH is a leucine derivative. | ||||||||||||||||||||
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Boc-N-Me-Leu-OH | 97.0% | Boc-N-Me-Leu-OH is a leucine derivative. | ||||||||||||||||||||
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N-(tert-Butoxycarbonyl)-N-methyl-D-leucine | 97.0% | N-(tert-Butoxycarbonyl)-N-methyl-D-leucine is a leucine derivative. | ||||||||||||||||||||
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(R)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-methylbutanoic acid | 97.0% | (R)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-methylbutanoic acid is a valine derivative. | ||||||||||||||||||||
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N-(tert-Butoxycarbonyl)-N-methyl-L-threonine | N-(tert-Butoxycarbonyl)-N-methyl-L-threonine is a threonine derivative. | |||||||||||||||||||||
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Boc-L-Ile-OH | 98.0% | Boc-L-Ile-OH is an isoleucine derivative. | ||||||||||||||||||||
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References
- [1]. Zhang W, et al. From Target-Oriented to Motif-Oriented: A Case Study on Nannocystin Total Synthesis. Molecules (Basel, Switzerland). 2020 Nov 15;25(22):5327.
- [2]. Pham THD, et al. Biosynthesis, Chemical Synthesis, and Pharmacological Evaluation of Lyngbyapeptin A as a GPCR Antagonist of Motilin, Cannabinoid, and Amylin Receptors. Journal of natural products. 2025 Nov 28;88(11):2610-2624.