52706-07-7
52706-07-7
Chemical Structure
Scillascillin
- CAS No.: 52706-07-7
- Formula:C17H12O6
- Molecular Weight:312.27
IUPAC Name: (R)-5,7-dihydroxy-6'H-spiro[chroman-3,5'-cyclobuta[4,5]benzo[1,2-d][1,3]dioxol]-4-one
InChIKey: SAXOGBBWXWKZKR-KRWDZBQOSA-N
SMILES: O=C1[C@]2(C3=C(C2)C=C(OCO4)C4=C3)COC5=CC(O)=CC(O)=C15
Biological Activity: Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively[1][2].
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Scillascillin | Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively. | |||||||||||||||||||||
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References
- [1]. Yoichiro Nishida, et al. A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chem Pharm Bull (Tokyo). 56, 7. [Content Brief]
- [2]. Chinthala Y, et al. Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria hyderabadensis. Pharmacognosy Res. 2014;6(4):303-305. [Content Brief]
