53-34-9
Chemical Structure
6α-Fluoroprednisolone
Synonym(s): Fluprednisolone
- CAS No.: 53-34-9
- Formula:C21H27FO5
- Molecular Weight:378.43
IUPAC Name: (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: MYYIMZRZXIQBGI-HVIRSNARSA-N
SMILES: C[C@]1(C2)[C@](CC[C@@](O)1C(CO)=O)([H])[C@@](C[C@@H]3F)([H])[C@@]([C@H]2O)([H])[C@](C3=CC4=O)(C=C4)C
Biological Activity: 6α-Fluoroprednisolone (Fluprednisolone) serves as the internal standard for Methylprednisolone (HY-B0260), Prednisolone (HY-17463), and Prednisone (HY-B0214). 6α-Fluoroprednisolone is an anti-inflammatory agent with anti-inflammatory activity. 6α-Fluoroprednisolone exhibits thymolytic activity. 6α-Fluoroprednisolone functions as a natriuretic agent[1][2].
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6α-Fluoroprednisolone | 6α-Fluoroprednisolone (Fluprednisolone) serves as the internal standard for Methylprednisolone (HY-B0260), Prednisolone (HY-17463), and Prednisone (HY-B0214). 6α-Fluoroprednisolone is an anti-inflammatory agent with anti-inflammatory activity. 6α-Fluoroprednisolone exhibits thymolytic activity. 6α-Fluoroprednisolone functions as a natriuretic agent. | |||||||||||||||||||||
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References
- [1]. A. Bowers, et al. Steroids‑CXXI synthesis of halogenated steroid hormones: 6α‑fluoro cortical hormones a new class of powerful corticoids, Tetrahedron. 7 (1959) 153‑162.
- [2]. N. Bodor, et al. A theoretical study of prednisolone, 6α‑fluoroprednisolone, 9α‑fluoroprednisolone, 6α,9α‑difluoroprednisolone and related compounds, Journal of Molecular Structure: THEOCHEM. 279 (1993) 59‑69.
