53053-08-0
53053-08-0
Chemical Structure
N3-Ph-NHS ester
- CAS No.: 53053-08-0
- Formula:C11H8N4O4
- Molecular Weight:260.21
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 4-azidobenzoate
InChIKey: LWAVGNJLLQSNNN-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)C2=CC=C(N=[N+]=[N-])C=C2
Biological Activity: N3-Ph-NHS ester (compound 133) is an organic synthesis intermediate and ADC linker used for the synthesis of antibody-drug conjugate (ADC) molecules[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N3-Ph-NHS ester | 99.83% | N3-Ph-NHS ester (compound 133) is an organic synthesis intermediate and ADC linker used for the synthesis of antibody-drug conjugate (ADC) molecules. | ||||||||||||||||||||
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4-N-Maleimidobenzoicacid-NHS | 99.14% | 4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond. | ||||||||||||||||||||
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DMABA NHS ester | 99.49% | DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products. | ||||||||||||||||||||
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DMABA-d6 NHS ester | DMABA-d6 NHS ester is the deuterium labeled DMABA NHS ester. | |||||||||||||||||||||
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Ald-Ph-NHS ester | 98.0% | Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). | ||||||||||||||||||||
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ANB-NOS | 98.02% | ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma. | ||||||||||||||||||||
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4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester | 99.50% | 4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester is a photoactivated bifunctional cross-linker. 4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester can be used for researching a strategy of rapid and accurate structure generation in support of antigen engineering programs. | ||||||||||||||||||||
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N-Succinimidyl (4-iodoacetyl)aminobenzoate | N-Succinimidyl (4-iodoacetyl)aminobenzoate is a biochemical reagent. | |||||||||||||||||||||
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2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride | 95.0% | 2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride is an intermediate of a radionuclide molecular probe targeting the CD4 receptor. 2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride serves as an imaging agent for heart transplant rejection. This CD4 probe is prepared by mixing leukocyte differentiation antigen 4 monoclonal antibody with a solution of 6-hydrazinylnicotinoyl succinimide ester hydrochloride, followed by extraction and reaction to obtain 6-hydrazinylnicotinate-leukocyte differentiation antigen 4 monoclonal antibody; this antibody is then mixed with N-tris (hydroxymethyl) glycine, stannous chloride and technetium for an oscillatory reaction. This CD4 probe exhibits high affinity for CD4+ T lymphocytes, along with the characteristics of high sensitivity and high specificity, enabling early diagnosis of acute rejection. | ||||||||||||||||||||
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2,5-Dioxopyrrolidin-1-yl methyl phthalate | 2,5-Dioxopyrrolidin-1-yl methyl phthalate is a cross-linking agent used for modification of proteins and peptides. 2,5-Dioxopyrrolidin-1-yl methyl phthalate is a reagent for introducing succinimide-activated esters that react with primary amines in proteins and peptides to form stable amide bonds. | |||||||||||||||||||||
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2,5-Dioxo-1-pyrrolidinyl 4-azido-2-hydroxybenzoate | 2,5-Dioxo-1-pyrrolidinyl 4-azido-2-hydroxybenzoate is a biochemical assay reagent. | |||||||||||||||||||||
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