537039-67-1
537039-67-1
Chemical Structure
UDP-6-azido-6-Deoxy-D-Glc
Synonym(s): UDP-α-6N3-glucose; 6-Azidoglucose-UDP
- CAS No.: 537039-67-1
- Formula:C15H23N5O16P2
- Molecular Weight:591.31
InChIKey: YLSUUMDTTUVTGP-JZMIEXBBSA-N
SMILES: O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@H]3O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H](O)[C@H]3O)(O)=O)(O)=O)O2)NC1=O
Biological Activity: UDP-6-azido-6-Deoxy-D-Glc (UDP-α-6N3-glucose; 6-Azidoglucose-UDP) is a UDP-sugar donor. UDP-6-azido-6-Deoxy-D-Glc is used for the selective labeling of 5-hmC in genomic DNA. UDP-6-azido-6-Deoxy-D-Glc enables glyco-diversification modification of saponin intermediates and click chemistry-based derivatization[1][2].
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UDP-6-azido-6-Deoxy-D-Glc | UDP-6-azido-6-Deoxy-D-Glc (UDP-α-6N3-glucose; 6-Azidoglucose-UDP) is a UDP-sugar donor. UDP-6-azido-6-Deoxy-D-Glc is used for the selective labeling of 5-hmC in genomic DNA. UDP-6-azido-6-Deoxy-D-Glc enables glyco-diversification modification of saponin intermediates and click chemistry-based derivatization. | |||||||||||||||||||||
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References
- [1]. Wang J, et al. Efficient chemoenzymatic synthesis of UDP-α-6-N3-glucose. Bioorg Med Chem Lett. 2019 May 1;29(9):1148-1151. [Content Brief]
- [2]. Hudson GA, et al. Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid ‑d‑Fucosylation. JACS Au. 2025 Dec 22;5(12):6011-6024. [Content Brief]
