53822-99-4
53822-99-4
Chemical Structure
Isofouquierol
- CAS No.: 53822-99-4
- Formula:C30H52O3
- Molecular Weight:460.73
InChIKey: ILQOLRWKVAXWJC-XVGAYARYSA-N
SMILES: C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@@](C)(O)C/C=C/C(C)(O)C)C)([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC1)C
Biological Activity: Isofouquierol is a selective inhibitor targeting nitric oxide (NO) production with anti-inflammatory activity. Isofouquierol blocks NO overproduction by inhibiting the inducible nitric oxide synthase (iNOS)-related pathway. Isofouquierol can be used in the study of inflammation-related diseases (such as chronic inflammation, immune disorders)[1][2].
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Isofouquierol | Isofouquierol is a selective inhibitor targeting nitric oxide (NO) production with anti-inflammatory activity. Isofouquierol blocks NO overproduction by inhibiting the inducible nitric oxide synthase (iNOS)-related pathway. Isofouquierol can be used in the study of inflammation-related diseases (such as chronic inflammation, immune disorders). | |||||||||||||||||||||
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References
- [1]. Pakhathirathien C, et al. Dammarane triterpenes from the hypocotyls and fruits of Ceriops tagal. J Nat Prod. 2005 Dec;68(12):1787-9. [Content Brief]
- [2]. Yoshikawa M, et al. Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Chem Pharm Bull (Tokyo). 2009 Sep;57(9):957-64. [Content Brief]
