53823-08-8
53823-08-8
Chemical Structure
Cascaroside A
- CAS No.: 53823-08-8
- Formula:C27H32O14
- Molecular Weight:580.53
InChIKey: MNAYRSRTNMVAPR-ZHVWOXMGSA-N
SMILES: O[C@H]1[C@](O[C@@H]([C@H]([C@@H]1O)O)CO)([H])[C@@]2([H])C3=CC=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C3C(C5=C(O)C=C(CO)C=C52)=O
Biological Activity: Cascaroside A is a naturally occurring anthraquinone glycoside compound. Cascaroside A can be hydrolyzed to yield barbaloin, which upon reaction with ferric chloride produces Aloe emodin (HY-N0189). Cascaroside A serves as a marker compound for the quantitative determination of anthraquinone content in the bark extract of Rhamnus purshiana DC.[1][2].
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Cascaroside A | Cascaroside A is a naturally occurring anthraquinone glycoside compound. Cascaroside A can be hydrolyzed to yield barbaloin, which upon reaction with ferric chloride produces Aloe emodin (HY-N0189). Cascaroside A serves as a marker compound for the quantitative determination of anthraquinone content in the bark extract of Rhamnus purshiana DC.. | |||||||||||||||||||||
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References
- [1]. Fairbairn J W. Vegetable purgatives containing anthracene derivatives: Part VII. The evaluation of cascara sagrada and its preparations. Journal of Pharmacy and Pharmacology, 1953, 5(1): 827-838.
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[2]. Souza K S, et al. Phytotoxicity and cytogenotoxic effects of extracts from the medicinal bark of Rhamnus purshiana DC. (Rhamnaceae). Journal of Toxicology and Environmental Health, Part A, 2025, 88(12): 505-517.
