53994-69-7
53994-69-7
Chemical Structure
7-Amino-3-chloro cephalosporanic acid
Synonym(s): 7-ACCA
- CAS No.: 53994-69-7
- Formula:C7H7ClN2O3S
- Molecular Weight:234.66
IUPAC Name: (6R,7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: OQSAFIZCBAZPMY-AWFVSMACSA-N
SMILES: O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](N)C1=O)O
Biological Activity: 7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an intermediate of β-lactam antibiotics and can be used to synthesize the cephalosporin Cefaclor (HY-B0198). 7-Amino-3-chloro cephalosporanic acid can be used in research on antibiotic synthesis[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Amino-3-chloro cephalosporanic acid | 99.35% | 7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an intermediate of β-lactam antibiotics and can be used to synthesize the cephalosporin Cefaclor (HY-B0198). 7-Amino-3-chloro cephalosporanic acid can be used in research on antibiotic synthesis. | ||||||||||||||||||||
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References
- [1]. Huang ZX, et al. Preparation of a novel nanobiocatalyst by immobilizing penicillin acylase onto magnetic nanocrystalline cellulose and its use for efficient synthesis of cefaclor. Chemical Engineering Journal. 2018 Aug 15;346:361-8.
- [2]. Wang L, et al. Two plate-based colorimetric assays for screening α-amino acid ester hydrolase with high synthesis/hydrolysis ratio. Enzyme and microbial technology. 2012 Jul 15;51(2):107-12.
- [3]. Miao S, et al. Antibiotic intermediates and antibiotics synergistically promote the development of multiple antibiotic resistance in antibiotic production wastewater. Journal of hazardous materials. 2024 Nov 05;479:135601.
- [4]. Zuo X, et al. Synergetic enzymatic reactive crystallization of cefaclor catalyzed by PGA. Journal of Molecular Liquids. 2024 Nov 15;414:126259.
- [5]. Jelisejevs D, et al. Pyrazolidinone-based peptidomimetic SARS-CoV-2 M inhibitors. Bioorganic & medicinal chemistry letters. 2023 Nov 15;96:129530.
