540-12-5
540-12-5
Chemical Structure
Ricinelaidic acid
- CAS No.: 540-12-5
- Formula:C18H34O3
- Molecular Weight:298.46
IUPAC Name: (R,E)-12-hydroxyoctadec-9-enoic acid
InChIKey: WBHHMMIMDMUBKC-XLNAKTSKSA-N
SMILES: OC(CCCCCCC/C=C/C[C@H](O)CCCCCC)=O
Biological Activity: Ricinelaidic acid, a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 μM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50=10 and 7 μM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ricinelaidic acid | Ricinelaidic acid, a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 μM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50=10 and 7 μM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
