5413-85-4
5413-85-4
Chemical Structure
4,6-Dichloropyrimidin-5-amine
- CAS No.: 5413-85-4
- Formula:C4H3Cl2N3
- Molecular Weight:164.00
IUPAC Name: 4,6-dichloropyrimidin-5-amine
InChIKey: NIGDWBHWHVHOAD-UHFFFAOYSA-N
SMILES: ClC1=C(N)C(Cl)=NC=N1
Biological Activity: 4,6-Dichloropyrimidin-5-amine is a pyrimidine derivative and synthetic intermediate. 4,6-Dichloropyrimidin-5-amine can be used for the preparation of Zika virus methyltransferase inhibitors, purine analogs and related derivatives[1][2][3].
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4,6-Dichloropyrimidin-5-amine | 99.94% | 4,6-Dichloropyrimidin-5-amine is a pyrimidine derivative and synthetic intermediate. 4,6-Dichloropyrimidin-5-amine can be used for the preparation of Zika virus methyltransferase inhibitors, purine analogs and related derivatives. | ||||||||||||||||||||
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References
- [1]. Del Río N, et al. Design, synthesis and evaluation of arylpurine-based sinefungin mimetics as zika virus methyltransferase inhibitors. RSC advances. 2025 Oct 02;15(44):37309-37324.
- [2]. Fatih Polat M, et al. Synthesis and cytotoxicity of novel 6,8,9-trisubstituted purine analogs against liver cancer cells. Bioorganic & medicinal chemistry letters. 2024 Jul 01;106:129775. [Content Brief]
- [3]. Dejmek M, et al. Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position. Archiv der Pharmazie. 2014 Jul;347(7):478-85.
