541550-19-0
541550-19-0
Chemical Structure
Apilimod
Synonym(s): STA 5326; LAM-002A free base; AIT-101
- CAS No.: 541550-19-0
- Formula:C23H26N6O2
- Molecular Weight:418.49
IUPAC Name: (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine
InChIKey: HSKAZIJJKRAJAV-KOEQRZSOSA-N
SMILES: CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1
Biological Activity: Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Apilimod | 99.80% | Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor. | ||||||||||||||||||||
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Apilimod (Standard) | ≥98% | Apilimod (Standard) is the analytical standard of Apilimod (HY-14644). This product is intended for research and analytical applications. Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor. | ||||||||||||||||||||
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