5521-58-4
5521-58-4
Chemical Structure
2-Amino-5-methylpyrazine
- CAS No.: 5521-58-4
- Formula:C5H7N3
- Molecular Weight:109.13
IUPAC Name: 5-methylpyrazin-2-amine
InChIKey: ZNQOALAKPLGUPH-UHFFFAOYSA-N
SMILES: NC1=NC=C(C)N=C1
Biological Activity: 2-Amino-5-methylpyrazine is an intermediate. 2-Amino-5-methylpyrazine can be used to synthesize LPAR1 antagonists and derivatives with antitumor and anti-inflammatory activities[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Amino-5-methylpyrazine | 99.72% | 2-Amino-5-methylpyrazine is an intermediate. 2-Amino-5-methylpyrazine can be used to synthesize LPAR1 antagonists and derivatives with antitumor and anti-inflammatory activities. | ||||||||||||||||||||
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References
- [1]. Rimoli MG, et al. Research on heterocyclic compounds. XXXVII. Synthesis and antiinflammatory activity of methyl-substituted imidazo [1, 2-a] pyrazine derivatives. European journal of medicinal chemistry. 1997 Jan 1;32(3):195-203.
- [2]. Myadaraboina S, et al. Structure activity relationship studies of imidazo [1, 2-a] pyrazine derivatives against cancer cell lines. European journal of medicinal chemistry. 2010 Nov 1;45(11):5208-16. [Content Brief]
- [3]. Pfefferkorn JA, et al. Designing glucokinase activators with reduced hypoglycemia risk: discovery of N, N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl) benzofuran-4-yloxy) pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus. MedChemComm. 2011 Aug 31;2(9):828-39.
- [4]. Jeffrey Roger Roppe, et al. Lpar1 antagonists and uses thereof. WO2023014908A1. WIPO (PCT). 2022-08-04.
