55266-18-7
Chemical Structure
MnTBAP chloride
- CAS No.: 55266-18-7
- Formula:C48H28ClMnN4O8
- Molecular Weight:879.15
InChIKey: XHVDAQLNUQLQKW-YKKPBKTHSA-K
SMILES: [Cl-][Mn+3]12([N](C(C=C3)=C4C(C=C5)=CC=C5C(O)=O)=C3C(C(C=C6)=CC=C6C(O)=O)=C7C=C8)[N-]7C8=C(C(C=C9)=CC=C9C(O)=O)C%10=[N]1C(C=C%10)=C(C(C=C%11)=CC=C%11C(O)=O)C%12=CC=C4[N-]2%12
Biological Activity: MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MnTBAP chloride | 98.0% | MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research. | ||||||||||||||||||||
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References
- [1]. Jing Yu, et al. MnTBAP Therapy Attenuates Renal Fibrosis in Mice With 5/6 Nephrectomy. Oxid Med Cell Longev. 2016;2016:7496930. [Content Brief]
- [2]. Qian Zhou, et al. MnTBAP Increases BMPR-II Expression in Endothelial Cells and Attenuates Vascular Inflammation. Vascul Pharmacol. 2016 Sep;84:67-73. [Content Brief]
