5531-98-6
5531-98-6
Chemical Structure
Atherosperminine
Synonym(s): Atherospermine
- CAS No.: 5531-98-6
- Formula:C20H23NO2
- Molecular Weight:309.40
IUPAC Name: 2-(3,4-dimethoxyphenanthren-1-yl)-N,N-dimethylethan-1-amine
InChIKey: UZZFAUDNCIFFPM-UHFFFAOYSA-N
SMILES: CN(C)CCC1=C2C=CC3=CC=CC=C3C2=C(OC)C(OC)=C1
Biological Activity: Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria[1][2].
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Atherosperminine | Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria. | |||||||||||||||||||||
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References
- [1]. Ayu Afiqah Nasrullah, et al. Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae). Molecules. 2013 Jul; 18(7): 8009–8017. [Content Brief]
- [2]. C H Lin, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma. Eur J Pharmacol. 1993 Jun 11;237(1):109-16. [Content Brief]
