55399-93-4
55399-93-4
Chemical Structure
(2S,3R,4S)-4-Hydroxyisoleucine
Synonym(s): (2S,3R,4S)-4-Hydroxy-L-isoleucine
- CAS No.: 55399-93-4
- Formula:C6H13NO3
- Molecular Weight:147.17
IUPAC Name: (2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoic acid
InChIKey: OSCCDBFHNMXNME-YUPRTTJUSA-N
SMILES: O[C@@H](C)[C@H](C)[C@H](N)C(O)=O
Biological Activity: (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(2S,3R,4S)-4-Hydroxyisoleucine | 98.0% | (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity. | ||||||||||||||||||||
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(2S,3R,4S)-4-Hydroxyisoleucine (Standard) | ≥98% | (2S,3R,4S)-4-Hydroxyisoleucine (Standard) is the analytical standard of (2S,3R,4S)-4-Hydroxyisoleucine (HY-W010271). This product is intended for research and analytical applications. (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity. | ||||||||||||||||||||
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DL-Threonine (Standard) | ≥98% | DL-Threonine (Standard) is the analytical standard of DL-Threonine. This product is intended for research and analytical applications. DL-Threonine, an essential amino acid, is a precursor of Glycine (HY-Y0966). DL-Threonine has the potential for the study of hypostatic leg ulceration. | ||||||||||||||||||||
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L-Threonine (Standard) | 99.39% | L-Threonine (Standard) is the analytical standard of L-Threonine. This product is intended for research and analytical applications. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed. | ||||||||||||||||||||
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L-Threonine-15N | 98.0% | L-Threonine-15N is the 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed. | ||||||||||||||||||||
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L-Threonine-13C4,15N | 99.98% | L-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed. | ||||||||||||||||||||
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L-Threonine-13C4 | 99.93% | L-Threonine-13C4 is the 13C labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed. | ||||||||||||||||||||
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4-Hydroxyisoleucine | 98.0% | 4-Hydroxyisoleucine is an orally active amino acid that can be isolated from fenugreek seeds. 4-Hydroxyisoleucine displays insulinotropic and antidiabetic properties. | ||||||||||||||||||||
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D-Allothreonine | 98.0% | D-Allothreonine is a non-proteinogenic amino acid that serves as a substrate for Pyridoxal phosphate (HY-B1744)-dependent D-threonine aldolase, being cleaved into Glycine (HY-Y0966) and acetaldehyde, and acts as a constituent of bioactive peptidyl natural products such as callipeltins, conferring protease resistance. D-Allothreonine is used in natural product synthesis and metabolic research. | ||||||||||||||||||||
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L-Allothreonine | 98.0% | L-Allothreonine (H-allo-Thr-OH) is a diastereomer of L-Threonine (HY-N0658) and belongs to non-proteinogenic amino acids. L-Allothreonine serves as a non-natural substrate for yeast Cystathionine β-Synthase (HY-E70078), which is used to investigate the substrate specificity and reaction mechanism of the enzyme. | ||||||||||||||||||||
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D-Threonine | 99.40% | D-Threonine (H-D-Thr-OH) is an important non-natural amino acid. D-Threonine serves as a chiral building block for the asymmetric synthesis of compounds. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde under the catalysis of D-threonine aldolase. | ||||||||||||||||||||
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(Rac)-Threonine | (Rac)-Threonine (Compound 19) is an amino acid derivative that can be found in the methanol (MeOH) extract of Rumex roseus L. The MeOH extract containing (Rac)-Threonine exhibits antioxidant and cytotoxic properties. | |||||||||||||||||||||
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References
- [1]. Shi X, et al. Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers. Sci Rep. 2017 Oct 20;7(1):13703. [Content Brief]
- [2]. Broca C, et al. 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion. Eur J Pharmacol. 2000 Mar 3;390(3):339-45. [Content Brief]
- [3]. Haeri MR, et al. Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic rats. Phytomedicine. 2012 May 15;19(7):571-4. [Content Brief]
