55612-21-0
55612-21-0
Chemical Structure
2'-Deoxy-2'-fluoro-5-iodouridine
Synonym(s): FIRU
- CAS No.: 55612-21-0
- Formula:C9H10FIN2O5
- Molecular Weight:372.09
IUPAC Name: methyl 2-(1H-tetrazol-1-yl)acetate
InChIKey: IPVFGAYTKQKGBM-UAKXSSHOSA-N
SMILES: O[C@H]1[C@@H](F)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
Biological Activity: 2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2'-Deoxy-2'-fluoro-5-iodouridine | 99.46% | 2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer. | ||||||||||||||||||||
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