55881-96-4
Chemical Structure
Sclareol glycol
- CAS No.: 55881-96-4
- Formula:C16H30O2
- Molecular Weight:254.41
IUPAC Name: 1-(2-hydroxyethyl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol
InChIKey: AIALTZSQORJYNJ-UHFFFAOYSA-N
SMILES: OCCC1C(C)(O)CCC2C(C)(C)CCCC12C
Biological Activity: Sclareol glycol is a blood-brain barrier-permeable, reversible adenylate cyclase (AC) activator. Sclareol glycol induces dose-dependent changes in body temperature, regulates convulsive seizures and spontaneous activity. Sclareol glycol interacts with GABAergic transmission, thereby affecting dopamine-related behaviors. Sclareol glycol can be used in studies related to convulsive seizures, aggressive responses, thermoregulation, etc[1][2][3][4].
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Sclareol glycol | 98.0% | Sclareol glycol is a blood-brain barrier-permeable, reversible adenylate cyclase (AC) activator. Sclareol glycol induces dose-dependent changes in body temperature, regulates convulsive seizures and spontaneous activity. Sclareol glycol interacts with GABAergic transmission, thereby affecting dopamine-related behaviors. Sclareol glycol can be used in studies related to convulsive seizures, aggressive responses, thermoregulation, etc. | ||||||||||||||||||||
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Sclareol glycol (Standard) | ≥98% | Sclareol glycol (Standard) is the analytical standard of Sclareol glycol (HY-N7007). This product is intended for research and analytical applications. Sclareol glycol is a blood-brain barrier-permeable, reversible adenylate cyclase (AC) activator. Sclareol glycol induces dose-dependent changes in body temperature, regulates convulsive seizures and spontaneous activity. Sclareol glycol interacts with GABAergic transmission, thereby affecting dopamine-related behaviors. Sclareol glycol can be used in studies related to convulsive seizures, aggressive responses, thermoregulation, etc. | ||||||||||||||||||||
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References
- [1]. Georgieva J, et al. Effects of the diterpene sclareol glycol on body temperature in rats. Methods and findings in experimental and clinical pharmacology. 1989 Apr;11(4):277-80. [Content Brief]
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[2]. Georgieva J. Effects of the diterpene sclareol glycol on convulsive seizures. Methods Find Exp Clin Pharmacol. 1989 May;11(5):335-40.
[Content Brief] - [3]. Georgieva JV, et al. Diterpene sclareol glycol inhibits clonidine-induced aggressive responses in mice. Pharmacology, biochemistry, and behavior. 1989 Nov;34(3):503-5. [Content Brief]
- [4]. Georgieva JV, et al. Influences of diterpene sclareol glycol on some dopamine related behavior. General pharmacology. 1991;22(2):331-5. [Content Brief]
