56-57-5
56-57-5
Chemical Structure
Nitrochin
Synonym(s): 4-NQO
- CAS No.: 56-57-5
- Formula:C9H6N2O3
- Molecular Weight:190.16
IUPAC Name: 4-nitroquinoline 1-oxide
InChIKey: YHQDZJICGQWFHK-UHFFFAOYSA-N
SMILES: O=[N+](C1=C2C=CC=CC2=[N+]([O-])C=C1)[O-]
Biological Activity: Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2].
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Nitrochin | 99.92% | Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway. | ||||||||||||||||||||
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Nitrochin (Standard) | ≥98% | Nitrochin (Standard) is the analytical standard of Nitrochin. This product is intended for research and analytical applications. Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway. | ||||||||||||||||||||
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References
- [1]. Mukherjee A, et al. Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. In Vivo. 2023 Mar-Apr;37(2):506-518. [Content Brief]
- [2]. Han H, et al. 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology. 2007 Feb 12;230(2-3):151-63. [Content Brief]
