56317-21-6
56317-21-6
Chemical Structure
Moracin M
- CAS No.: 56317-21-6
- Formula:C14H10O4
- Molecular Weight:242.23
IUPAC Name: 5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol
InChIKey: LHPRYOJTASOZGJ-UHFFFAOYSA-N
SMILES: OC1=CC(C2=CC3=CC=C(O)C=C3O2)=CC(O)=C1
Biological Activity: Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Moracin M | 98.99% | Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity. | ||||||||||||||||||||
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Moracin M (Standard) | ≥98% | Moracin M (Standard) is the analytical standard of Moracin M. This product is intended for research and analytical applications. Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity. | ||||||||||||||||||||
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References
- [1]. Chen SK, et al. Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor. Bioorg Med Chem Lett. 2012 May 1;22(9):3261-4. [Content Brief]
- [2]. Lee JH, et al. Moracin M inhibits airway inflammation by interrupting the JNK/c-Jun and NF-κB pathways in vitro and in vivo. Eur J Pharmacol. 2016;783:64-72. [Content Brief]
