56437-16-2
Chemical Structure
3-Carboxy-6-hydroxycoumarin
- CAS No.: 56437-16-2
- Formula:C10H6O5
- Molecular Weight:206.15
IUPAC Name: 6-hydroxy-2-oxo-2H-chromene-3-carboxylic acid
InChIKey: SLPOZBYDRWPSBE-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC(O)=CC=C2OC1=O)O
Biological Activity: 3-Carboxy-6-hydroxycoumarin is an intermediate in organic syntheses[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Carboxy-6-hydroxycoumarin | 99.93% | 3-Carboxy-6-hydroxycoumarin is an intermediate in organic syntheses. | ||||||||||||||||||||
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UBP608 (Standard) | ≥98% | UBP608 (Standard) is the analytical standard of UBP608 (HY-100667). This product is intended for research and analytical applications. UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders. | ||||||||||||||||||||
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3-Acetylcoumarin | 97.0% | 3-Acetylcoumarin (Compound 4) has acaricidal activity against Tetranychus cinnabarinus. | ||||||||||||||||||||
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3,5-Dihydroxy-2-naphthoic acid | 3,5-Dihydroxy-2-naphthoic acid is a Naphthoic acid derivative. Naphthoic acid is a NMDA receptor allosteric modulator. | |||||||||||||||||||||
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3-Cyanoumbelliferone | 98.0% | 3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM. | ||||||||||||||||||||
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3-Carboxy-7-Hydroxycoumarin | 99.10% | 3-Carboxy-7-Hydroxycoumarin is a 7-hydroxycoumarin (umbelliferone) fluorescent dye and antibody-conjugated labeling agent with UV excitation properties. 3-Carboxy-7-Hydroxycoumarin undergoes deprotonation in neutral-to-alkaline environments, producing strong blue fluorescence. The absorption/emission maxima of 3-Carboxy-7-Hydroxycoumarin are 386/448 nm. 3-Carboxy-7-Hydroxycoumarin is applicable for related research such as fluorescent probe synthesis and covalent protein labeling. | ||||||||||||||||||||
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Esculetin (Standard) | 99.91% | Esculetin (Standard) is the analytical standard of Esculetin. This product is intended for research and analytical applications. Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities. | ||||||||||||||||||||
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4,7-Dihydroxycoumarin | 98.25% | 4,7-Dihydroxycoumarin is an EGFR inhibitor, estrogen receptor inhibitor, and progesterone receptor inhibitor. 4,7-Dihydroxycoumarin against breast cancer cells with an IC50 velue of 18.36 μg/mL. 4,7-Dihydroxycoumarin can be used for the research of breast cancer. | ||||||||||||||||||||
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Coumarin-3-carboxylic Acid | 99.93% | Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. | ||||||||||||||||||||
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3-Acetyl-6-bromocoumarin | 98.0% | 3-Acetyl-6-bromocoumarin is a coumarin. 3-Acetyl-6-bromocoumarin exhibites potent antioxidant activity at 56%. | ||||||||||||||||||||
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3-Acetyl-7-Hydroxycoumarin | 95.17% | 3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis. | ||||||||||||||||||||
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