56488-58-5
56488-58-5
Chemical Structure
Tizolemide
- CAS No.: 56488-58-5
- Formula:C11H14ClN3O3S2
- Molecular Weight:335.83
SMILES: O=S(N)(C1=CC(C2(N(C)/C(SC2)=N/C)O)=CC=C1Cl)=O
Biological Activity: Tizolemide is a sulphonamide diuretic compound that has alkaline properties and is cleared by a tubular transport system. Tizolemide induces changes of passive transport components across the basolateral membrane of isolated frog skin[1][2].
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Tizolemide | Tizolemide is a sulphonamide diuretic compound that has alkaline properties and is cleared by a tubular transport system. Tizolemide induces changes of passive transport components across the basolateral membrane of isolated frog skin. | |||||||||||||||||||||
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References
- [1]. Beermann B, et al. Diuretic effect and pharmacokinetics of tizolemide in subjects with normal and decreased renal function. Clin Nephrol. 1983 Mar;19(3):124-31. [Content Brief]
- [2]. Nagel W, et al. Tizolemide-induced changes of passive transport components across the basolateral membrane of isolated frog skin. Pflugers Arch. 1981 Sep;391(3):219-25. [Content Brief]
